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Nanotechnology – A drug delivery promise for scar-less wound healing.

1/1/2015

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Nanotechnology represents an ‘Innovative direction’. It’s not the future as it’s already present in the pharmaceuticals, natural products realm and it’s expected to grow with time.

Injectable and dermatology spheres have successfully employed Nanotechnology to product development. Yet, there is still a wide gap in wound- healing dermatology.

The wound healing process consists of four highly integrated and over lapping phases- hemostasis, inflammation, proliferation and time remodeling. For a wound to heal successfully, all four phases of this process must occur in the proper sequence, at a specific time and continue for specific duration at optimal intensity.

Conventional wound-healing products, in majority of instances, do tend to leave scar behind. This is the case both with pharmaceutical and natural products.

For example Curcumin derived from spice turmeric, has traditionally been known to be excellent with wound healing even when administered in the raw powder form.  For a formulator, the challenge is water- insoluble nature of turmeric as well as the staining property of curcumin.

Applying Nanotechnology to formulation development of turmeric products, is expected to circumvent the difficulties inherent in curcumin administration, enabling delivery of this therapeutic substance.  Furthermore, curcumin in a Nano vesicle will assist clear infection as well as accelerate wound healing by sitting more evenly on the wound bed.

Research findings have shown that the growth of tissue and extent of scar formation can be controlled by modulating the stress at a wound site. And Nanotechnology shows promise for delivering many advanced wound- healing agents.

With Nanotechnology, you can have multiple therapeutic agents in one platform that can work synergistically in wound therapy. For example, combining turmeric with a collagen regenerating/ remodeling ingredient will further augment the healing process, wound repair and tissue regeneration and bring- on scar less wound healing.

However, the key to using Nanotechnology correctly to pharmaceuticals and natural products is having a complete understanding of - Which Nano materials can accelerate wound- healing, how and when to use them and which wound healing agents to incorporate viz. immunomodulatory, anti-microbials anti-inflammatory etc.

Nanotechnology is indeed a “magic bullet’ in developing safe, effective and targeted science based products.


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#Nanotechnology  #AdvancesInNanotechnologyForPharmaceuticals  #TurmericForWoundHealing
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