Innovation Mantra: Think Big, Start Small, Scale-up Fast
|
Idea Management is an important and integral part of Innovation Management. There are two schools of thought about idea generation and its management. First, out-of-the box thinking and second, inside-the-box thinking.
Out-of-the-box thinking as the name suggests is seamless creativity. While inside-the-box thinking means there is a boundary within which ideas are generated and managed. Wider the boundary, deeper gets the creativity. |
And if more ideas have to grow from 'being on paper' to becoming 'a commercialized product', inside-the-box thinking is the way to go. Because, for a business there is a budget to follow, expenses to limit, ROI to gain and investors to take care of. Every penny spent on innovation is accounted for i.e. where profits aren’t earned, the R&D expenditure gets written-off. And the objective is always to get the most out of the buck.
Inside-the-box thinking essentially means, innovation is done with a target product profile in mind. The aim is to generate large number of ideas to maximize number of potential ideas-to-product pathways. The picture below depicts innovation management via inside-the-box idea generation.
Once an idea qualifies for becoming a new product candidate, it must successfully pass through the various stages of product development thru obtaining market approval and subsequent launch, to find its crown in the marketplace.
Inside-the-box thinking essentially means, innovation is done with a target product profile in mind. The aim is to generate large number of ideas to maximize number of potential ideas-to-product pathways. The picture below depicts innovation management via inside-the-box idea generation.
Once an idea qualifies for becoming a new product candidate, it must successfully pass through the various stages of product development thru obtaining market approval and subsequent launch, to find its crown in the marketplace.
|
Not all ideas gain ‘new product candidate’ status. So, what happens to the ideas, that do not get selected. Do they get dumped permanently? The answer is No.
Let's analyze the ideas further- Usually, ideas get rejected because of three main reasons- a. Technically idea commercialization is not possible. b. Profit wise the ideas are not feasible. c. The company is not keen to go for such a new product at this point of time. Hence, let's first segregate the rejected ideas into three buckets as per the above classification and then review them one-by-one. A. Technically idea commercialization is not possible: Ideas that are not technically feasible now can become great candidates later. A classic example of this is Sildenafil citrate tablet. This drug candidate was first evaluated as a treatment for chest-pain. Later, the company found an alternate use of the drug candidate and channeled this molecule thru the development pipeline to launch as Viagra- rest is history! B. Profit wise the ideas are not feasible: The second lot comprises of those ideas that seem not feasible in terms of profitability. Meaning technically, they may be good, but cannot be commercialized because of high cost. One of the classic example for this is- the Microwave oven. |
|
Microwave oven was first invented in the 1940s, around world war II era. The first commercialized microwave oven was huge, weighing 750 pounds and costed $2000 USD. Obviously, it did not sell well. The company worked on the technical aspects and the first domestic microwave was introduced in 1955. And that did not sell too. After many design changes, microwave oven gained access to our homes in 1967 and by 1975, they were in full demand.
A point to note here is that microwave oven invention was both accidental and EVOP (Evolutionary Operation) product development. Also, note the development timeline, from 1940 to 1955 to 1967 to 1975. i.e. 27 to 35 years from being an 'idea' to 'profitable' commercialization!
It is well-known that EVOP drains money. To avoid such bleed, concept of Innovation Management took shape. I shall be writing more about innovation management in a separate blogpost. For now let us visit the third lot of rejected ideas.
A point to note here is that microwave oven invention was both accidental and EVOP (Evolutionary Operation) product development. Also, note the development timeline, from 1940 to 1955 to 1967 to 1975. i.e. 27 to 35 years from being an 'idea' to 'profitable' commercialization!
It is well-known that EVOP drains money. To avoid such bleed, concept of Innovation Management took shape. I shall be writing more about innovation management in a separate blogpost. For now let us visit the third lot of rejected ideas.
C. Company is not keen to go for such a new product at this point of time:
Now, let us consider the third lot of ideas- those ideas which the company is not keen to go for at this point of time.
Such ideas must be worked upon in the lab to develop a small prototype. While prototyping, ensure that you build-in anti-counterfeit measures in your product. Then file a provisional patent application to stake claim to your idea and simultaneously block competition. After filing a provisional patent application, you have 12 months to file final PCT patent specification. Additionally, you get thirty months (from date of priority filing) to enter national phase i.e. do national phase patent applications in the PCT countries of your choice.
Hence, the company gets close to 30 months to scout for buyers who would be interested to license your product. Since a prototype as well as the patent is available (for the invention), you stand to gain better licensing fees at the negotiation table. Also, resources need not be pumped-in immediately, as product development, process validation, scale-up and other related activities can take place over 12 to 30 months timeframe. This has dual advantages- first, R&D budget can be better managed, and second, R&D infrastructure can be better utilized.
Now, let us consider the third lot of ideas- those ideas which the company is not keen to go for at this point of time.
Such ideas must be worked upon in the lab to develop a small prototype. While prototyping, ensure that you build-in anti-counterfeit measures in your product. Then file a provisional patent application to stake claim to your idea and simultaneously block competition. After filing a provisional patent application, you have 12 months to file final PCT patent specification. Additionally, you get thirty months (from date of priority filing) to enter national phase i.e. do national phase patent applications in the PCT countries of your choice.
Hence, the company gets close to 30 months to scout for buyers who would be interested to license your product. Since a prototype as well as the patent is available (for the invention), you stand to gain better licensing fees at the negotiation table. Also, resources need not be pumped-in immediately, as product development, process validation, scale-up and other related activities can take place over 12 to 30 months timeframe. This has dual advantages- first, R&D budget can be better managed, and second, R&D infrastructure can be better utilized.
Moreover, provisional and/or final PCT patents being intellectual property can be mortgaged on a short-term basis to banks or other financial institutions, to secure funds which in turn may be pumped-in to conduct research work or use it for other areas of the business. The philosophy of Innovation Management is to ensure, every penny spent on R&D must bring-in good return on investment (ROI) both in terms of profits and company reputation.
The goal of Innovation Management is to turn ideas into profit, block competition and stop counterfeits. |
There are multiple pathways for conducting idea and innovation management successfully. The content presented above is one such pathway. Also, the choice of idea and innovation management pathways depend on various factors such as- industry vertical, product mix, operating markets, corporate goals and more. Therefore, selecting the best pathway which will yield faster ROI with a first-mover advantage is crucial.
Your choice of idea, innovation management pathway and its flawless execution will determine your business's very existence, growth and resilience. However, an important question to introspect is- Are you building an idea and innovation management strategy which is the best for your organization?
Your choice of idea, innovation management pathway and its flawless execution will determine your business's very existence, growth and resilience. However, an important question to introspect is- Are you building an idea and innovation management strategy which is the best for your organization?
Innovation should meet a real purpose. Just innovating for the sake of innovation, leads to waste of capital and resources.
To know more about how idea-innovation management can help your company expand its product offerings, increase profit and earnings per share for investors, checkout my insights below.
Here you will find articles on Innovation management, Innovation strategies, How to build a culture of innovation, Design Thinking, Innovation tools, Innovation methodologies such as DFSS, TRIZ etc, Experimental designs, Ideation and idea management, building innovation and R&D capabilities, building new product portfolio, Research management, R&D leadership, Continuous improvement for R&Ds etc.
Here you will find articles on Innovation management, Innovation strategies, How to build a culture of innovation, Design Thinking, Innovation tools, Innovation methodologies such as DFSS, TRIZ etc, Experimental designs, Ideation and idea management, building innovation and R&D capabilities, building new product portfolio, Research management, R&D leadership, Continuous improvement for R&Ds etc.
Popular Articles on Product Portfolio Development, Innovation Management, Research Management and R&D Leadership:
Idea Management: Master key to innovate and capture profit.Idea Management is an important and integral part of Innovation Management. There are two schools of thought...
Read More |
How to invalidate a patent?US Supreme Court turned away Biogen's appeal of a lower court's decision to invalidate the patent in a ruling that helped clear the way for Mylan's generic version of Tecfidera. Read More
|
Transform your business with an effective patent strategyIn this post, I shall touch upon few different types of patents, when and how can they be filed and what benefits do they offer to a business. Read More
|
New Age Product Development to Reduce Supply Chain CostsReducing procurement, supply chain logistics is an omnipresent to-do issue for business leaders, pandemic or otherwise, but more so in today’s Read More
|
What Is Divisional Patent Application?A divisional patent application is a type of patent application that claims the subject matter of a previously filed application. Read More
|
Kaizen For Cost Reduction - A Continuous Improvement Case StudyLearn how to use Kaizen to manage intellectual property and reduce patent filing costs by 20% or more. Read More
|
How to Handle Patent InfringementThere are several ways to deal with patent infringements...
Read More |
Organoids As Models of the Human BrainThe successful transplantation of human brain cells into a rodent's brain has made it possible for scientists to study the complex brain circuits and psychiatric disorders. Read More
|
Kaizen For Innovation Management & Productivity Improvement Of A Hospital In France: A Healthcare Continuous Improvement Case StudyHealthcare is a service-based industry sector. Unlike other industries, healthcare has a lot of human angle to it, since it deals with patients Read More
|
Business Turnaround and Innovation Management in a Global Contract Research Organization- A Case StudyA Global Contract Research Organization (CRO) was sick and on the verge of being sold out. The management wanted to give a final shot for its revival prior to potential sell off. Read More
|
Innovation Management, Just-in-time and Kaizen Case Study in a Multi-National Pharmaceutical Company Working on ANDA Para III and IV Drug ProductsAn multi-national pharmaceutical company had an ambitious goal of new product introductions Read More
|
How to identify 505 (b)(2) drug product development opportunities- An Innovation Management Case StudyA Global Pharmaceutical Contract Research Organization (CRO) wanted to start a new division that could develop products via the 505 (b)(2) pathway. Read More
|
Developing ANDA Para II and III Drug Products via QbD (Quality by Design) : Innovation Management Case StudyA multi-national bio-pharma company wanted to develop Three new products via QbD methodology for US (ANDA para II and III) and Canada markets. Read More
|
8 Steps to Becoming a Customer- Centric Organization.Customer-centric approach comprises of sequential and collaborative efforts at understanding the voice of the customer (VoC). Read More
|
Dos and Don’ts Of Rapid InnovationOrganizations, right at the outset, need to have complete clarity about the path they wish to take regarding innovation. Read More
|
Innovation is not an initiative. It’s a business process !It has been found that typically 75% of industry based innovations belong to process innovation, while only 25% share is attributed to product innovation. Read More
|
5 Attributes for Customer-Centric Innovation.Customer-centric approach breeds customer loyalty, increases market share and profit. Read More
|
9 Key areas for businesses to bring new products fast to market.First-mover advantage is the ultimate aim behind any new product development. Unlike popular belief, new product development is Read More
|
3D Printed drones for distribution- supply chain logistics process improvement.3D Printing is revolutionizing distribution and supply chain logistics processes. Besides saving zillions of dollars, Read More
|
Nanotechnology – A drug delivery promise for scar-less wound healing.Nanotechnology represents an ‘Innovative direction’. It’s not the future as it’s already present in the pharmaceuticals, natural products realm and it’s expected to grow with time. Read More
|
Role of Benchmarking in Business Process Improvement/ Business Process RedesignBenchmarking is a business term that defines the comparison of a business against others in terms of understanding where the business stands Read More
|
Innovation Strategy- mantra of money making!An effective innovation strategy depends more on an organization’s innovation processes, tools and culture than how much it spends on R&D. Read More
|
New avenues available for smoking cessation: E cigarettes !Currently there are several options available for people interested in smoking cessation- tablets, capsules, patches, mouth dissolve films, chewing gums Read More
|
FDA Approves First-Ever Human Test Of Embryonic Stem Cell-Based Therapy.The USFDA has approved "the world's first authorized test in people of a therapy derived from human embryonic stem cells. Read More
|
FDA Approves First Implantable Miniature Telescope to Improve Sight of AMD patients.The Implantable Miniature Telescope (IMT) to improve vision in some patients with end-stage age-related macular degeneration (AMD). Read More
|
FDA Approves Novel Asthma Treatment.USFDA recently approved the "first non-drug asthma treatment- Alair." According to the developer the procedure known as "bronchial thermoplasty" Read More
|
What is the Future of medicine ? What are the lessons from 60 years of pharmaceutical innovation?If the NME (New Molecular Entity) output is constant, the only way to grow Read More
|
How to transform businesses via portfolio management- Part 1Product mix or product portfolio is one of the important parameters impacting successful business transformation. Read More
|
How to transform businesses via portfolio management - Part 2
Portfolio project management technique plays the role of a gear in the overall portfolio management. Its function starts right from identifying new products for the portfolio, thru Read More
|
How to transform businesses via portfolio management- Part 3 Broadly, new product development can happen via three development pathways namely Read More
|
How to transform businesses via portfolio management- Part 4The fourth important parameter of building a profitable portfolio is introspecting and assessing your marketing and sales process(es) efficiency and effectiveness. Read More
|
Gefapixant can become a 'game changer' in treating people with persistent cough, reveals studyA new drug Gefapixant 45 mg twice per day is the first treatment to show efficacy with an acceptable safety profile in phase 3 clinical trials for refractory chronic cough Read More
|
Healthcare process efficiency improvement with blood bank robotThis fully automated system can take over manual tasks such as sorting by blood Read More
|
Design Thinking for Service IndustriesDesign Thinking and rapid prototyping is not just for the Manufacturing industries … Service industries also stand to benefit from it. Here’s how Read More
|
Apotex succeeds in getting a NOCA recent Federal Court decision highlighted the differences in prohibition proceedings under the Patented Medicines (Notice of Compliance) Regulations (the NOC Regulations) and impeachment actions under the Patent Act. Read More
|
Research and development in the 21st century: Web-enabled innovation comes of age.High-tech organizations that live and die by new product development have exploited the Web to speed communications and share information. Read More
|
What is Machine Learning?Machine learning is a sub-field of artificial intelligence and deals with a machine's capability to self-learn based on its surroundings and imitate intelligent human behavior. Read More
|
Unpredictable but not surprising !The Federal Court released reasons in Novo Nordisk Canada Inc. et al. v. Cobalt Pharmaceuticals Inc. et al. (2010 FC 746; "Novo Nordisk")) finding Cobalt's allegation of obviousness justified Read More
|
Federal court refuses patent granted based on prior artThe Federal Court of Appeal put an end to the disparity in the jurisprudence surrounding whether a patentee could obtain a patent to a medicine Read More
|
Eli Lilly Canada v. Novopharm Ltd : Canadian Patent Act contains no reference to invalidate selection patents –Lilly sued Novopharm for infringement under Canadian Patent No. 2,041,113, a selection patent for the compound olanzapine (sold under the brand name Zyprexa) Read More
|
Apotex Vs Pfizer in Lipitor patent challenge : An interesting case studyThe litigation between Pfizer and Apotex over Apotex's ANDA for a generic version of Lipitor (atorvastatin calcium) presents the fairly typical scenario of a later ANDA filer Read More
|
IP Australia tightens patent rules ?IP Australia is addressing this problem through changes to 'case management' practice rather than any legislative changes. Read More
|
US Supreme Court Hedges Its Bets On Business Methods- Canadian Businesses, beware !Blessing of ‘Business Patents’ in US will affect you.The US Supreme Court recently issued its long-awaited decision in the case of Bilski v Kappos which is considered to be Read More
|
United Arab Emirates: Major Changes To UAE IP Laws AnnouncedThe UAE government has announced proposals to introduce major amendments to the IP regime in the UAE. These proposed changes will have an impact across three areas Read More
|
Are selection patents new business challenges for researchers and companies like?Once a discovery is made, there is often a rush to patent as much of the discovery as it allows and then some. Patent practitioners seek to protect new compounds by filing patent applications Read More
|
Australian Innovation Patent Advantage - Ignore it at Your Potential PerilThe Australian patent system has a unique beast called the "innovation patent". Under the Australian patent system it is possible to obtain both standard patents and innovation patents. Read More
|
Practical Considerations And Strategies In Drafting U.S. Patent ApplicationsUnder the U.S. patent law, a patent not only serves as a technical disclosure for an invention to be protected, but also defines the boundaries of exclusive rights granted by Read More
|
Apotex Vs Astra Zeneca : Court Finds AstraZeneca Patent To Esomeprazole (NEXIUM) Invalid For Lack Of Sound Prediction And ObviousnessBrought by AstraZeneca under the provisions of the Patented Medicines (Notice of Compliance) Regulations for an order prohibiting the Minister of Health from issuing a notice of compliance Read More
|
Australia: Not All Patent Protection Is Equal - Beware IP-Related ScamsRecently, there has been an increase in so-called "scams" involving apparent IP-related companies sending misleading letters to applicants and owners of IP rights in an attempt to extract money from those persons. Read More
|
Italy: Disclosing Generics Applications : AIFA Heading For Greater Transparency?The Italian Medicines Agency (AIFA) has issued new guidelines on its future policy on the disclosure of generics (Gxs) applications. AIFA stated that "further to consultations with Italian Read More
|
Patent Abstracts for Canadian patent filings must be made available in both official languages i.e. English and FrenchFrédéric Picard brought an application in the Federal Court under subsection 77(1) of the Official Languages Act against the Canadian Intellectual Property Office and the Commissioner of Patents claiming Read More
|
Canada´s Federal Court Of Appeal Limits Damages Available To Delayed GenericsMerck Frosst Canada Inc. v. Apotex, Inc., the Federal Court of Appeal released an important decision limiting the range of damages available in actions under section 8 of the Patented Medicines Read More
|
Canadian Patent Disclosure Requirements ClarifiedThe Federal Court clarified the disclosure requirements in patent drafting. This case is important to patent owners as it makes clear that misinformation, lack of information or insufficient information to support Read More
|
CIPO's New Draft Guidelines Could Result In Higher Disclosure Standards For Canadian PatentsThe Canadian Intellectual Property Office (CIPO) has released a further update to the Manual of Patent Office Practice (MOPOP), an administrative document of CIPO Read More
|
Australian Patent Office: Patent term extension available if it has pharmaceutical characteristicsThe Australian Patent Office has handed down a significant decision in the land down under, which impacts the type of pharmaceutical subject matter that is eligible for term extension. Read More
|
Canadian patent law : An introductionThe article (as series) mentions a brief about Canadian patent law. Reader is advised to consider this article for information purpose only and not as legal advise of any kind. Hope you find the articles informative. Read More
|
Canada and the U.S : Differences in Patent LawA patent may be invalidated if fees are incorrectly paid at the small entity rate. New regulations that are in their final stages of approval will require that small entity payments are accompanied Read More
|
Pages from the history- A comparison of patent laws world wide- IVGulf Cooperation Council: Includes the following countries viz. Kuwait, Qatar, Oman, Saudi Arabia, Bahrain, United Arab Emirates. Read More
|
Pages from the history- A comparison of patent laws world wide -IIITo comply with its TRIPS obligation to grant product patents for agrochemicals and pharmaceuticals, India has enacted the Patents Amendment Ordinance 2005 Read More
|
Pages from the history- A comparison of patent laws world wide- IIEnforcement of patent right depends on the province and locality where the action is brought. Better results have been seen in Beijing. Read More
|
Pages from the history- A comparison of patent laws world wide- IEquivalent patent in a country that has similar novelty, inventive step and industrial applicability requirements as Argentina. Read More
|
Role of “Conceptual Data Modeling” in Business Process ManagementConceptual data modeling refers to a summary type of information modeling that is typically used for projects regarding data Read More
|
The Patent PendulumIn the past 12 months, two significant decisions (one in Canada, the other in the United States) have the potential to dramatically recalibrate the scope of patent protection for Read More
|
Three important Canadian Patent decisions in December 2009In Canada, linkage regulations similar to the Hatch-Waxman Act in the U.S. ensure that generics manufacturers have to address relevant patents listed on the Patent Register Read More
|
Canadian patent law : Patent description and exampleThe nature of the invention must be defined in the disclosure and the manner in which the invention is to be carried out, must be described. In the case of a machine (for example, a computer) Read More
|
Canadian patent law : claimsA patent may have many claims, each defining the invention in different words and describing it broad or narrow functional language. Read More
|
Canadian patent law : types of claimsA Jepson claim recites the prior art in the preamble, uses the transitional phrase "the improvement comprising" and then recites the new elements or improvements to the prior device or method. Read More
|
New Zealand: Prior Art Searching: The Importance Of Due Diligence In R&D ProcessesTime and costs spent searching existing scientific publications and patent registers can avoid costly mistakes when acquiring or licensing technology from a third party or before undertaking Read More
|
Big pharma kisses its blockbuster years goodbyeIndustry giants are facing major new challenges as patents run out on many of the drugs that have kept them in clover. Read More
|
Is ‘hybrid model ' a good long-term strategy for drug-makers?Innovator drug companies have been actively wooing generic drug-makers, to have a foot in the innovative and generic segments of the pharmaceutical landscape. Read More
|
Mexican Supreme Court Decides on Broad Interpretation of Linkage Regulations.Mexico enacted linkage regulations to avoid the granting of marketing authorizations in violation of patent rights. The system created by these regulations is far less elaborate than Read More
|
Federal court of appeals upholds data protection laws...The Federal Court of Appeal dismissed the appeals brought by Apotex Inc. and the Canadian Generic Pharma Association challenging the validity of the Data Protection Regulations Read More
|
Changes To Canadian Patent Law ...Canada and the European Union (EU) are negotiating an intellectual property (IP) agreement, as part of a broader free trade agreement, which may have great impact Read More
|
China clarifies patent law rules...New legislation was promulgated recently following the recent revision of the PRC Patent Law ("New Patent Law"). "Matching rules" will affect the initiative of patent Read More
|
Importance of prior art search in product development - A Case studyTime and costs spent searching existing scientific publications and patent registers can avoid costly mistakes when acquiring or licensing technology Read More
|
United Kingdom: Deadline for Filing of Divisional Patent ApplicationsThe European Patent Office (EPO) amended the rules regarding the filing of divisional applications. Under the amended Rule 36 EPC Read More
|
Life cycle management and Intellectual property management for pharmaceutical generics.Brand Teams Protect Their Products With an Average of Five Distinct Strategies, According to Cutting Edge Information Read More
|
New Chinese Patent law.As a major emerging economy, China is striving to become an innovative country while facing major concerns such as accessibility to and affordability of medicines. Read More
|
Mexican Patent Office Excludes Formulation Patents from Linkage GazetteThe Mexican Trademark and Patent Office (IMPI) made available through its website the new edition of the Linkage Gazette (Mexican health and IP Read More
|
Kaizen For Innovation And Product Development: A Continuous Improvement Case StudyIn this case study, Kaizen-ing helped in improving eyedrop dropper design and its process of making. Read More
|
Launching and growing a start-up R&D unit- A case study
A SE Asian bio-pharma company that sold white labeled products wanted to start indigenous research facility. They also wanted to improve Read More
|
What are stem cells and what do they do?Stem cells are cells that are found in many different places in the human body. They can be found in the bone marrow Read More
|
Pharmaceutical patent cliff ...In today’s global economy, there is an increasing convergence of intellectual property and finance. Wall Street is grappling with how, exactly, to recognize the true value of a firm’s intellectual property, Read More
|
Top 15 drug patent losses for 2013Pharmaceutical researcher Evaluate Pharma estimates there are $290 billion of sales at risk from patent expirations between this year and 2018. Read More
|
Mistake-Proofing Pharmaceutical Product Development, Manufacturing and Logistics, Cost Savings via Poka Yoke Do you have any of the following complaints such as - R&D is slow, doesn’t give ... Read More
|
Modernize regulatory information management to improve operational excellence in life science organizationsOne of the many ways to improve operational excellence in life science organizations is ...
Read More |
Stem Cell Research and Manufacturing ChallengesAs the field of stem cell research and manufacturing continues to evolve, challenges remain. These include unregulated processes, scaling up production, epigenetic analysis etc. Read More
|
Valsartan, Irbesartan, Losartan Product Recalls- What are the Lessons for Pharmaceutical Industry?Since September last year, news of *SARTAN drug recalls are doing the rounds Read More
|
Nanotechnology in Mucosal Drug Delivery SystemsA new generation of drug delivery systems is being created as a result of the ability to design nano particles and their matrixes. Nano particles are very small molecules Read More
|
Innovative Strategies and Models for R&D Success.Over the last quarter of the twentieth century, medical research made substantial advances in defining our understanding of diseases, their etiologies, and the biochemical pathways through which they were mediated. Read More
|
Lean Innovation, Hoshin Kanrii and Six Sigma (as DFSS) for Product Design, Development and Manufacture via 3D Printing; a Case StudyLean Innovation, Hoshin Kanrii and Six Sigma (DFSS- design for six sigma) for product design, development Read More
|
USFDA Unveils Two Draft Guidelines For Generic Development Of Transdermal And Topical Dosage FormsThe United States Food and Drug Administration (USFDA) today 9th October 2018, Read More
|
Intranasal administration route for protein & peptide mucosal delivery. Due to its unique physiology and ready accessibility, the nasal cavity is an attractive delivery site for the systemic administration of therapeutics. The nasal membrane or mucosa Read More
|
Carriers used in Drug Targeting- Niosomes non-ionic surfactant vesicles are similar to liposomes and can be prepared with cholesterol, a surfactant such as polysorbates (tweens) or sorbitanesters of fatty acids (spans) and water. Read More
|
Continuous Improvement in Cancer Therapy & Healthcare System Services Today I read a report in Stat News about the first ‘digital pill’ that has been rolled out at a Cancer Treatment center in Minnesota US. Read More
|
BUCCAL DELIVERY OF PEPTIDES- I The presence of a smooth and relatively immobile surface for placement of a bioadhesive dosage form, the buccal region appears to be more suitable Read more
|
Advances in pharmaceutical research- use of nanotechnology as therapeutic platforms for disease management.New nanoparticles deliver bigger drug payload. Read More
|
Pulmonary route for mucosal drug delivery- I Choosing the lungs to deliver drugs beyond airways is not new. Nicotine and other anesthetics have been delivered to the blood stream this way for many years. Read More
|
Pulmonary route for mucosal drug delivery- IIDry powder inhalers (DPIs) are breath-actuated devices, by virtue of the fact that the kinetic energy imparted to the drug comes from the patient inhaling Read More
|
Medical robots market is expected to reach USD 11.4 Billion by 2020 at CARG of 22.2% Medical robots, an emerging field in healthcare is causing a paradigm shift in healthcare as it improves Read More
|
FDA Approves First-Ever Human Test Of Embryonic Stem Cell-Based Therapy.
The USFDA has approved "the world's first authorized test in people of a therapy... Read More
|
Novel Oral Controlled Drug Delivery SystemsTechnology in the field of controlled delivery has gone forward at a rapidly accelerating pace and promises many new and exciting developments. Read More
|
Mucosal Drug Delivery Systems- Part 1: Formulation Considerations
Mucoadhesive drug delivery systems utilize the property of bioadhesion.. Read More
|
Formulation considerations in mucosal drug delivery-II The rational approach for developing innovative polypeptide delivery system must therefore initially address two basic questions Read More
|
Formulation Considerations In Mucosal Drug Delivery Systems - IIISeveral test methods have been reported for studying mucoadhesives. These tests are necessary not only to screen a large number of candidate mucoadhesives Read More
|
Formulation considerations in mucosal drug delivery- IVTo ensure efficacy and safety of a drug product, the active compound and its degraded product(s) must be quantified to determine the expiry period Read More
|
Controlled Release Drug Delivery Systems.The deployment of drugs within the body is becoming more precise with the advent of rate-controlled dosage forms Read More
|
Analytical considerations of mucosal drug delivery systemsAs is the case with classical chemical substances, drug and diagnostic products Read More
|
Mistake-Proofing Pharmaceutical Products: What can we learn from Valsartan, Losartan and Irbesartan recalls? First Valsartan, now Irbesartan formulations are going thru a recall. Read More
|
Gambia cough syrup tragedy: How can we stop such catastrophe?Dozens of child deaths have been reported recently in African country The Gambia. The deaths are allegedly linked to cough syrups ... Read More
|
How to Boost Manufacturing Capability in Life Sciences OrganizationsOne of the biggest challenges facing life sciences organizations today is the need to scale their operations... Read More
|
