Popular articles on Drugs-in-the-Making:
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Continuous Improvement for Pharmaceutical R&D

Return on pharmaceutical R&D investment is steadily dropping over the past decade from 10.1 % in 2010 to 1.8 % in 2019. ​Read More

Continuous Improvement for Drug Industry: Part 6: Selecting the right R&D digitalization platform.

Continuous improvement in R&D via digitalization...Read More

Transitioning from Computer Software Validation (CSV) to Computer Software Assurance (CSA)

Having a transition strategy is essential... Read More

How to Boost Manufacturing Capability in Life Sciences Organizations

One of the biggest challenges facing life sciences organizations today is the need to scale their operations... Read More

Out of Specification Impurity and Non-Compliance to Manufacturing Standards Continue to Haunt Pharmaceuticals- The Lupin Story.  Here's One Way to Correct the Mess 

​Out of specification impurity ... Read More

Mistake-Proofing Pharmaceutical Product Development, Manufacturing and Logistics, Cost Savings via Poka Yoke ​

Do you have any of the following complaints such as - R&D is slow, doesn’t give ... Read More

Modernize regulatory information management to improve operational excellence in life science organizations

One of the many ways to improve operational excellence in life science organizations is ...
Read More

Stem Cell Research and Manufacturing Challenges

As the field of stem cell research and manufacturing continues to evolve, challenges remain. These include unregulated processes, scaling up production, epigenetic analysis etc. ​Read More

Valsartan, Irbesartan, Losartan Product Recalls- What are the Lessons for Pharmaceutical Industry?​

Since September last year, news of *SARTAN drug recalls are doing the rounds Read More

​Nanotechnology in Mucosal Drug Delivery Systems

​A new generation of drug delivery systems is being created as a result of the ability to design nano particles and their matrixes. Nano particles are very small molecules Read More

​Innovative Strategies and Models for R&D Success.

​Over the last quarter of the twentieth century, medical research made substantial advances in defining our understanding of diseases, their etiologies, and the biochemical pathways through which they were mediated. Read More

​Lean Innovation, Hoshin Kanrii and Six Sigma (as DFSS) for Product Design, Development and Manufacture via 3D Printing; a Case Study

Lean Innovation, Hoshin Kanrii and Six Sigma (DFSS- design for six sigma) for product design, development Read More​

USFDA Unveils Two Draft Guidelines For Generic Development Of Transdermal And Topical Dosage Forms

​The United States Food and Drug Administration (USFDA) today 9th October 2018, Read More

Intranasal administration route for protein & peptide mucosal delivery. ​

Due to its unique physiology and ready accessibility, the nasal cavity is an attractive delivery site for the systemic administration of therapeutics. The nasal membrane or mucosa Read More ​

Carriers used in Drug Targeting- ​

Niosomes non-ionic surfactant vesicles are similar to liposomes and can be prepared with cholesterol, a surfactant such as polysorbates (tweens) or sorbitanesters of fatty acids (spans) and water. Read More ​

Continuous Improvement in Cancer Therapy & Healthcare System Services ​

Today I read a report in Stat News about the first ‘digital pill’ that has been rolled out at a Cancer Treatment center in Minnesota US. ​Read More

BUCCAL DELIVERY OF PEPTIDES- I ​

The presence of a smooth and relatively immobile surface for placement of a bioadhesive dosage form, the buccal region appears to be more suitable Read more

​Advances in pharmaceutical research- use of nanotechnology as therapeutic platforms for disease management.

New nanoparticles deliver bigger drug payload. Read More 

Pulmonary route for mucosal drug delivery- I ​

​Choosing the lungs to deliver drugs beyond airways is not new. Nicotine and other anesthetics have been delivered to the blood stream this way for many years. Read More 

​Pulmonary route for mucosal drug delivery- II

​Dry powder inhalers (DPIs) are breath-actuated devices, by virtue of the fact that the kinetic energy imparted to the drug comes from the patient inhaling Read More

Medical robots market is expected to reach USD 11.4 Billion by 2020 at CARG of 22.2% ​

​Medical robots, an emerging field in healthcare is causing a paradigm shift in healthcare as it improves Read More

FDA Approves First-Ever Human Test Of Embryonic Stem Cell-Based Therapy.

The USFDA has approved "the world's first authorized test in people of a therapy... Read More​

​Novel Oral Controlled Drug Delivery Systems

Technology in the field of controlled delivery has gone forward at a rapidly accelerating pace and promises many new and exciting developments. Read More

Mucosal Drug Delivery Systems- Part 1: Formulation Considerations ​

​Mucoadhesive drug delivery systems utilize the property of bioadhesion.. Read More

Formulation considerations in mucosal drug delivery-II ​

The rational approach for developing innovative polypeptide delivery system must therefore initially address two basic questions Read More

​Formulation Considerations In Mucosal Drug Delivery Systems - III

Several test methods have been reported for studying mucoadhesives. These tests are necessary not only to screen a large number of candidate mucoadhesives Read More

Formulation considerations in mucosal drug delivery- IV​

​To ensure efficacy and safety of a drug product, the active compound and its degraded product(s) must be quantified to determine the expiry period Read More

​Controlled Release Drug Delivery Systems.

​The deployment of drugs within the body is becoming more precise with the advent of rate-controlled dosage forms Read More

​Analytical considerations of mucosal drug delivery systems

As is the case with classical chemical substances, drug and diagnostic products ​Read More

Mistake-Proofing Pharmaceutical Products: What can we learn from Valsartan, Losartan and Irbesartan recalls? ​

First Valsartan, now Irbesartan formulations are going thru a recall. Read More

Gambia cough syrup tragedy: How can we stop such catastrophe?

Dozens of child deaths have been reported recently in African country The Gambia. The deaths are allegedly linked to cough syrups ... Read More